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PMID: 396446 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Identification of a mutation affecting an alanine-alpha-ketoisovalerate transaminase activity in Escherichia coli K-12.

Molecular & general genetics : MGG ·Vol. 176 ·No. 1 ·1979-10-02 ·Pages 147-9

Falkinham JO

Abstract

A mutation affecting alanine-alpha-ketoisovalerate transaminase activity has been shown to be cotransducible with ilv gene cluster. The transaminase deficiency results in conditional isoleucine auxotrophy in the presence of alanine.

MeSH Terms
Alanine/metabolism Alanine Transaminase/genetics,metabolism Chromosome Mapping Escherichia coli/enzymology,genetics Keto Acids Mutation Pentanoic Acids Transaminases/metabolism
Chemicals
Keto Acids Pentanoic Acids Transaminases Alanine Transaminase Alanine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Falkinham J O
References (9)
9 references, click to expand
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    J Bacteriol. 1976 Jun;126(3):1194-206 PMID: 780343
  2. The asparagine synthetase of Escherhic coli. I. Biosynthetic role of the enzyme, purification, and characterization of the reaction products.
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  3. Isoleucine and valine metabolism of Escherichia coli. XVI. Pattern of multivalent repression in strain K-12.
    J Bacteriol. 1968 May;95(5):1680-4 PMID: 4870282
  4. Transamination in Escherichia coli.
    J Biol Chem. 1953 Feb;200(2):591-604 PMID: 13034817
  5. Antipolarity in the ilv operon of Escherichia coli K-12.
    J Bacteriol. 1969 Jun;98(3):1179-94 PMID: 4892370
  6. Regulation of transaminase C synthesis in Escherichia coli: conditional leucine auxotrophy.
    J Bacteriol. 1974 Nov;120(2):715-23 PMID: 4616947
  7. CHROMOSOMAL ABERRATIONS ASSOCIATED WITH MUTATIONS TO BACTERIOPHAGE RESISTANCE IN ESCHERICHIA COLI.
    J Bacteriol. 1965 Jan;89:28-40 PMID: 14255678
  8. Escherichia coli K-12 mutant with alternate requirements for vitamin B6 or branched-chain amino acids and lacking transaminase C activity.
    J Bacteriol. 1977 Apr;130(1):566-8 PMID: 323243
  9. Origin of replication, oriC, or the Escherichia coli chromosome on specialized transducing phages lambda asn.
    Mol Gen Genet. 1978 Apr 17;160(3):287-95 PMID: 353492
Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00334306
Published
1979-10-02
Pages
147-9
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00334306
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