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PMID: 3965370 Published · ppublish English Journal Article

Histological appearances of oesophagus, antrum and duodenum and their correlation with symptoms in patients with a duodenal ulcer.

Gut ·Vol. 26 ·No. 1 ·1985-01-00 ·Pages 95-100

Earlam RJ, Amerigo J, Kakavoulis T, Pollock DJ

Abstract

Clinical data and histology from the oesophagus, gastric antrum, and duodenum were collected from 36 patients undergoing surgery for duodenal ulcer. Gastritis was present in 94% of the patients (25% of atrophic type), oesophagitis in 72% and duodenitis in 39%. Abnormal biopsies were present from all three sites in 33% of the patients. Only one patient showed three normal biopsies. The low incidence of duodenitis does not support the theory that duodenitis is part of the same spectrum as duodenal ulcer. Heartburn was related to the presence of gastritis (100%) and oesophagitis (76%) but not to duodenitis (52%). No relationship was found between the length of history, severity of pain, and histological abnormalities.

MeSH Terms
Adult Aged Duodenal Ulcer/complications,pathology Duodenitis/complications Duodenum/pathology Esophagitis/complications Esophagus/pathology Female Gastritis/complications Gastroesophageal Reflux/complications Heartburn/complications Humans Male Middle Aged Pyloric Antrum/pathology
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Earlam R J
Amerigo J
Kakavoulis T
Pollock D J
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Article Info
Journal
Gut
Abbr.
Gut
ISSN
0017-5749
DOI
10.1136/gut.26.1.95
Published
1985-01-00
Pages
95-100
Language
English
Region
England
NLM ID
2985108R
PMCID
PMC1432390
Subset
IM
External Links
PubMed source DOI: 10.1136/gut.26.1.95 PMC Full Text View journal details
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