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PMID: 3982437 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

A ninth complementation group in xeroderma pigmentosum, XP I.

Mutation research ·Vol. 145 ·No. 3 ·1985-05-00 ·Pages 217-25

Fischer E, Keijzer W, Thielmann HW, Popanda O, Bohnert E, Edler L, Jung EG, Bootsma D

Abstract

A new complementation group of excision-deficient xeroderma pigmentosum (XP) is described in 2 patients living in the F.R.G. Dermatological, ophthalmological and neurological symptoms of XP are presented together with DNA repair characteristics such as unscheduled DNA synthesis, colony-forming ability and alkaline elution studied in cultured fibroblasts. The results are compared to normal controls.

MeSH Terms

Adolescent Adult Carcinogens/pharmacology Cells, Cultured DNA/biosynthesis DNA Repair/drug effects,radiation effects Female Fibroblasts/metabolism,pathology Genetic Complementation Test Humans Male Ultraviolet Rays Xeroderma Pigmentosum/genetics

Chemicals

Carcinogens DNA

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Fischer E

Keijzer W

Thielmann H W

Popanda O

Bohnert E

Edler L

Jung E G

Bootsma D

Article Info

Journal

Mutation research

Abbr.

Mutat Res

ISSN

0027-5107

DOI

10.1016/0167-8817(85)90030-6

Published

1985-05-00

Pages

217-25

Language

English

Region

Netherlands

NLM ID

0400763

Subset

External Links

PubMed source DOI: 10.1016/0167-8817(85)90030-6 View journal details

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A ninth complementation group in xeroderma pigmentosum, XP I.

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