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PMID: 3985365 Published · ppublish English Journal Article

Cytodifferentiation of the interstitial cells of Cajal related to the myenteric plexus of mouse intestinal muscle coat. An E.M. study from foetal to adult life.

Anatomy and embryology ·Vol. 171 ·No. 2 ·1985-00-00 ·Pages 163-9

Faussone-Pellegrini MS

Abstract

The cytodifferentiation of the interstitial cells of Cajal (Type I) related to the myenteric plexus of the mouse intestinal muscle coat was studied in foetuses at term, neonates not yet fed, suckling animals, weaning animals and adult animals. In foetuses at term, interstitial cells of Cajal and their precursor cells are not identifiable. In neonates not yet fed, presumed precursor cells of the interstitial cells of Cajal, i.e. ICC-blasts, can be identified as cells surrounding the developing myenteric plexus and interposed between the circular and longitudinal muscle layers. These ICC-blasts are poorly differentiated but, like the adult interstitial cells, are always related to nerve endings and possess large and numerous mitochondria. In suckling animals these cells gradually develop, and are fully differentiated only after the end of the weaning period.

MeSH Terms
Animals Animals, Newborn/anatomy & histology Animals, Suckling/anatomy & histology Cell Differentiation Fetus/anatomy & histology Intestines/innervation Mice/anatomy & histology Microscopy, Electron Muscles/innervation Myenteric Plexus/cytology,ultrastructure Weaning
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Faussone-Pellegrini M S
References (15)
15 references, click to expand
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Article Info
Journal
Anatomy and embryology
Abbr.
Anat Embryol (Berl)
ISSN
0340-2061
Published
1985-00-00
Pages
163-9
Language
English
Region
Germany
NLM ID
7505194
Subset
IM
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