Abstract
The cytodifferentiation of the interstitial cells of Cajal (Type I) related to the myenteric plexus of the mouse intestinal muscle coat was studied in foetuses at term, neonates not yet fed, suckling animals, weaning animals and adult animals. In foetuses at term, interstitial cells of Cajal and their precursor cells are not identifiable. In neonates not yet fed, presumed precursor cells of the interstitial cells of Cajal, i.e. ICC-blasts, can be identified as cells surrounding the developing myenteric plexus and interposed between the circular and longitudinal muscle layers. These ICC-blasts are poorly differentiated but, like the adult interstitial cells, are always related to nerve endings and possess large and numerous mitochondria. In suckling animals these cells gradually develop, and are fully differentiated only after the end of the weaning period.
MeSH Terms
Animals
Animals, Newborn/anatomy & histology
Animals, Suckling/anatomy & histology
Cell Differentiation
Fetus/anatomy & histology
Intestines/innervation
Mice/anatomy & histology
Microscopy, Electron
Muscles/innervation
Myenteric Plexus/cytology,ultrastructure
Weaning
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Faussone-Pellegrini M S
References (15)
15 references, click to expand
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