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PMID: 3988347 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Chemical characterization of Chlamydia trachomatis lipopolysaccharide.

Infection and immunity ·Vol. 48 ·No. 2 ·1985-05-00 ·Pages 573-5

Nurminen M, Rietschel ET, Brade H

Abstract

The group-specific antigen of Chlamydia trachomatis serotype L2 was chemically analyzed. It is composed of typical lipopolysaccharide (LPS) components, i.e., D-glucosamine, long-chain 3-hydroxy fatty acids, 2-keto-3-deoxyoctonic acid, and phosphate in a molar ratio of approximately 2:5:3:2.6, respectively, resembling enterobacterial LPS of the Re chemotype. For the first time, 3-hydroxydocosanoic acid (3-OH C22:0) was found as an LPS constituent.

MeSH Terms
Chlamydia trachomatis/classification,immunology Enterobacteriaceae/immunology Fatty Acids/analysis Glucosamine/analysis Lipopolysaccharides/analysis Phosphates/analysis Sugar Acids/analysis
Chemicals
Fatty Acids Lipopolysaccharides Phosphates Sugar Acids 2-keto-3-deoxyoctonate Glucosamine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Nurminen M
Rietschel E T
Brade H
References (20)
20 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
Published
1985-05-00
Pages
573-5
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC261381
Subset
IM
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