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PMID: 4007265 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Partial rescue of embryos from two maternal-effect neurogenic mutants by transplantation of wild-type ooplasm.

Developmental biology ·Vol. 110 ·No. 1 ·1985-07-00 ·Pages 264-7

LaBonne SG, Mahowald AP

Abstract

We show that embryos produced by Drosophila females homozygous for the maternal-effect neurogenic mutations almondex and pecanex can be partially rescued by microinjection of wild-type ooplasm. In addition, we demonstrate that these mutations fully complement one another with respect to this assay, as they do by classical genetic criteria. Finally, we show that embryos from both mutations cease to be rescuable after the establishment of the syncytial blastoderm. The significance of these results for our understanding of the neurogenic phenotype is discussed.

MeSH Terms
Animals Blastoderm/cytology Cytoplasm/transplantation Drosophila/embryology,genetics Embryo, Nonmammalian/cytology Female Genes, Lethal Microinjections Mutation Oocytes/cytology Phenotype
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
LaBonne S G
Mahowald A P
Article Info
Journal
Developmental biology
Abbr.
Dev Biol
ISSN
0012-1606
Published
1985-07-00
Pages
264-7
Language
English
Region
United States
NLM ID
0372762
Subset
IM
Grants
NICHD NIH HHS · HD07104 · United States
NICHD NIH HHS · HD17607 · United States
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