The release of lyso-PAF from guinea-pig lungs.

European journal of pharmacology ·Vol. 112 ·No. 2 ·1985-06-07 ·Pages 281-4

Parente L, Fitzgerald M, De Nucci G, Moncada S

Abstract

Lyso-PAF was detected after ionophore challenge in the effluent of lungs of guinea-pigs exposed to oxygen and perfused through the pulmonary circulation as well as of control lungs perfused through the airways. Lyso-PAF is probably the inactive metabolite of PAF-acether which could not, itself, be detected in the lung effluents.

MeSH Terms

Animals Guinea Pigs In Vitro Techniques Lung/drug effects,metabolism Male Oxygen/toxicity Perfusion Platelet Activating Factor/analogs & derivatives,metabolism

Chemicals

O-deacetyl platelet activating factor Platelet Activating Factor Oxygen

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Parente L

Fitzgerald M

De Nucci G

Moncada S

Article Info

Journal

European journal of pharmacology

Abbr.

Eur J Pharmacol

ISSN

0014-2999

DOI

10.1016/0014-2999(85)90511-4

Published

1985-06-07

Pages

281-4

Language

English

Region

Netherlands

NLM ID

1254354

Subset

External Links

PubMed source DOI: 10.1016/0014-2999(85)90511-4 View journal details

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The release of lyso-PAF from guinea-pig lungs.

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