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PMID: 40428101 Published · epublish English Journal Article

A Computational Study on Renal Artery Anatomy in Patients Treated with Fenestrated or Branched Endovascular Aneurysm Repair.

Bioengineering (Basel, Switzerland) ·Vol. 12 ·No. 5 ·2025-05-01

Wang Y, Sang Y, Li W, Zhou M, Zhao Y, He X, Wang C, Li X, Liu Z

Abstract

(1) Background: Renal artery occlusion after F/B EVAR for abdominal aortic aneurysm is a serious complication that may require re-intervention, and understanding the hemodynamic mechanisms by which it occurs is essential to optimize the surgical procedure. (2) Methods: We used computational fluid dynamics (CFD) to analyze the impact of various parameters on blood flow. Theoretical vascular models were constructed based on the common dimensions and angles of aortic stents and branch arteries in clinical practice. Actual case models were constructed from CT image data of six patients treated with F/B-EVAR. Data were collected for analysis after simulation and calculation by FLUENT software. (3) Results: Theoretical model simulations showed that a larger tilt angle of the branch stent, smaller branch entry depth, and larger branch stent diameter were beneficial for blood flow. In the case models, a significant difference in the tilt angle of the renal artery stents was observed between the high- and low-flow groups, while the differences in entry depth and branch stent diameter were not significant. Occluded renal arteries had lower WSS values than patent ones. (4) Conclusions: This study offers valuable guidance for optimizing stent placement in F/B EVAR to mitigate renal artery occlusion risk.

Keywords
F/B EVAR branch flow hemodynamics prosthetic vascular stent
作者与单位
共 9 位作者,点击展开单位 / ORCID
Wang Yuzhu ORCID
Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Sang Yuna
School of Astronautics, Harbin Institute of Technology, Harbin 150080, China.
Li Wendong
Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Zhou Minjie
Research and Development Department, Nanjing Cloudure Medical Co., Ltd., Nanjing 211200, China.
Zhao Yushun
School of Astronautics, Harbin Institute of Technology, Harbin 150080, China. | National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Harbin Institute of Technology, Harbin 150080, China.
He Xiaodong
National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Harbin Institute of Technology, Harbin 150080, China.
Wang Chao
School of Astronautics, Harbin Institute of Technology, Harbin 150080, China. | National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Harbin Institute of Technology, Harbin 150080, China.
Li Xiaoqiang
Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Liu Zhao
Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Article Info
Journal
Bioengineering (Basel, Switzerland)
Abbr.
Bioengineering (Basel)
ISSN
2306-5354
Published
2025-05-01
电子出版
2025-00-01
Language
English
Country/Region
Switzerland
NLM ID
101676056
基金资助
Jiangsu Provincial Social Development Project · BE2019604
National Natural Science Foundation of China · 82370520
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