Home LiteratureArticle Details

PMID: 4052068 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Comparison of human and bovine brain derived heparin-binding growth factors.

Biochemical and biophysical research communications ·Vol. 131 ·No. 2 ·1985-09-16 ·Pages 586-92

Lobb RR, Strydom DJ, Fett JW

Abstract

Two growth factors have been purified to homogeneity from human brain using heparin affinity chromatography. They have apparent molecular weights of 17 Kd and 18 Kd. Their amino acid compositions differ, but are similar to those of the two heparin-binding growth factors present in bovine neural tissue. These results suggest that the heparin-binding growth factors in neural tissue can be grouped into two distinct classes.

MeSH Terms

Acetonitriles Amino Acids/analysis Animals Biological Assay Brain Chemistry Cattle Cell Division Cell Line Chromatography, Affinity Chromatography, High Pressure Liquid Electrophoresis, Polyacrylamide Gel Growth Substances/isolation & purification,metabolism,pharmacology Heparin/metabolism Humans Mice Mice, Inbred BALB C

Chemicals

Acetonitriles Amino Acids Growth Substances Heparin acetonitrile

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Lobb R R

Strydom D J

Fett J W

Article Info

Journal

Biochemical and biophysical research communications

Abbr.

Biochem Biophys Res Commun

ISSN

0006-291X

DOI

10.1016/0006-291x(85)91277-x

Published

1985-09-16

Pages

586-92

Language

English

Region

United States

NLM ID

0372516

Subset

External Links

PubMed source DOI: 10.1016/0006-291x(85)91277-x View journal details

Analysis Services

Comparison of human and bovine brain derived heparin-binding growth factors.

Contact

WeChat Official Account