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PMID: 40760964 Published · aheadofprint English Journal Article

Technological advances in acupoint thread embedding treatment: Effects on NIHSS score, Serum SIRT1, HIF-1α, and macrophage efferocytosis in stroke patients.

Li M, Xie W, Lv Q, He M, Zou H, Hong M, Pang H, Cai J, Shi J, Huang W

Abstract

BackgroundAcupoint thread embedding treatment (ATET) is a traditional therapeutic approach used in stroke rehabilitation.ObjectiveTo explore the application of ATET in combination with modern medical technology, examining its effects on neurological function and key serum biomarkers in stroke patients.MethodsA total of 108 stroke patients were randomly assigned to ATE treatment group (n = 52) and Control Group (n = 56). Various parameters including baseline characteristics, levels of inflammatory markers, macrophage efferocytosis-related factors, the National Institutes of Health Stroke Scale (NIHSS) scores, therapeutic efficacy, and adverse events were assessed and compared between the two groups.ResultsA significant improvement in NIHSS scores was observed in the treatment group compared to the control group. Additionally, serum levels of SIRT1, HIF-1α, and macrophage efferocytosis-related factors were significantly altered, suggesting that ATET may influence biological pathways involved in stroke recovery.ConclusionThe application of ATET, supported by advanced diagnostic technologies, shows promising effects in stroke rehabilitation. This study highlights the potential for integrating traditional therapies with modern medicine to improve clinical outcomes in stroke patients.

Keywords
Acupoint thread embedding treatment HIF-1α NIHSS score SIRT1 macrophage efferocytosis-related factors stroke
作者与单位
共 10 位作者,点击展开单位 / ORCID
Li Min
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Xie Wanyi
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Lv Qingrui
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
He Meitang
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Zou Hanhong
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Hong Miaoying
Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Pang Hanyan
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Clinical Laboratory, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Cai Jingchao
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Shi Jianshuang
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Huang Wenhao
The Fifth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China. | Department of Acupuncture and Rehabilitation, Guangdong Second Traditional Chinese Medicine, Guangzhou, China.
Article Info
Journal
Technology and health care : official journal of the European Society for Engineering and Medicine
Abbr.
Technol Health Care
ISSN
1878-7401
Published
2025-08-05
电子出版
2025-00-05
页码
9287329251363433
Language
English
Country/Region
United States
NLM ID
9314590
勘误 / 撤稿关联
ExpressionOfConcernIn
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