Chlorinated biphenyl induction of aryl hydrocarbon hydroxylase activity: a study of the structure-activity relationship.

Aminopyrine N-Demethylase/metabolism Animals Aryl Hydrocarbon Hydroxylases/biosynthesis Benzopyrene Hydroxylase/biosynthesis Binding Sites/drug effects Binding, Competitive Chick Embryo Cytochrome P-450 Enzyme System/metabolism Cytosol/metabolism Enzyme Induction/drug effects In Vitro Techniques Liver/metabolism,ultrastructure Male Mice Mice, Inbred C57BL Mice, Inbred DBA Polychlorinated Biphenyls/pharmacology Polychlorinated Dibenzodioxins/pharmacology Rats Structure-Activity Relationship

Polychlorinated Dibenzodioxins Cytochrome P-450 Enzyme System Polychlorinated Biphenyls Benzopyrene Hydroxylase Aryl Hydrocarbon Hydroxylases Aminopyrine N-Demethylase