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PMID: 40887193 Published · ppublish chi English Abstract Journal Article

[Simulation analysis of adaptability of large airborne negative pressure isolation cabin to aviation conditions].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi ·Vol. 42 ·No. 4 ·2025-08-25 ·页码 775-781

Guo L, Li F, Jiang L, Du H, Xue B, Yong W, Jiang Y, Zhang M

Abstract

In order to solve the problems of difficult test, high cost and long cycle in the development of large-scale airborne negative pressure isolation system, the simulation analysis of negative pressure response characteristics is carried out around various aviation conditions such as aircraft ascending, leveling and descending, especially rapid decompression, based on the computational fluid dynamics (CFD) method. The results showed that the isolation cabin could achieve -50 Pa pressure difference environment and form a certain pressure gradient. The exhaust air volume reached the maximum value in the early stage of the aircraft's ascent, and gradually decreased with the increase of altitude until it was level flying. In the process of aircraft descent, the exhaust fan could theoretically maintain a pressure difference far below -50 Pa without working; Under the special condition of rapid pressure loss, it was difficult to deal with the rapid change of low pressure only by the exhaust fan, so it was necessary to design safety valve and other anti-leakage measures in the isolation cabin structure. Therefore, the initial stage of aircraft ascent is the key stage for the adjustment and control of the negative pressure isolation system. By controlling the exhaust air volume and adjusting parameters, it can adapt to the change of low pressure under normal flight conditions, form a relatively stable negative pressure environment, and meet the needs of biological control, isolation and transport.

Keywords
Computational fluid dynamics Flight conditions Infectious diseases Isolation cabin Negative pressure
MeSH 主题词
Aircraft Computer Simulation Aviation/instrumentation Humans Hydrodynamics Air Pressure Equipment Design Pressure
作者与单位
共 8 位作者,点击展开单位 / ORCID
Guo Lei
Air Force Medical Center, Air Force Medical University, PLA, Beijing 100142, P. R. China.
Li Falin
Air Force Medical Center, Air Force Medical University, PLA, Beijing 100142, P. R. China.
Jiang Lang
Air Force Medical Center, Air Force Medical University, PLA, Beijing 100142, P. R. China.
Du Haibo
Air Force Medical Center, Air Force Medical University, PLA, Beijing 100142, P. R. China.
Xue Bingjie
Air Force Medical Center, Air Force Medical University, PLA, Beijing 100142, P. R. China.
Yong Wei
Air Force Medical Center, Air Force Medical University, PLA, Beijing 100142, P. R. China.
Jiang Yuanyuan
Air Force Medical Center, Air Force Medical University, PLA, Beijing 100142, P. R. China.
Zhang Muzhe
Air Force Medical Center, Air Force Medical University, PLA, Beijing 100142, P. R. China.
Article Info
Journal
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Abbr.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
ISSN
1001-5515
Published
2025-08-25
页码
775-781
Language
chi
Country/Region
China
NLM ID
9426398
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