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PMID: 4098430 Published · ppublish English Journal Article

Electrn microscopic observations on virus-like particles associated with SH antigen.

Journal of virology ·Vol. 6 ·No. 5 ·1970-11-00 ·Pages 685-9

Jokelainen PT, Krohn K, Prince AM, Finlayson ND

Abstract

The structural aspects of SH antigen-containing particles were investigated. These studies confirmed the existence of a large spherical particle (ca. 43 nm) and smaller (ca. 20 nm) rod- and sphere-shaped particles. The large particle consists of an outer and inner membrane and a core of "nucleic acid" as seen by positive staining techniques. The outer membrane of the large particle appears to be similar to that of the 20-nm diameter spheres and rods known to possess the SH antigen.

MeSH Terms
Acute Disease Antigens Carrier State/immunology,microbiology Chronic Disease Hepatitis B/immunology,microbiology Hepatitis B virus/immunology,isolation & purification Humans Microscopy, Electron Phosphotungstic Acid Potassium Permanganate Staining and Labeling Uranium
Chemicals
Antigens Potassium Permanganate Phosphotungstic Acid Uranium
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Jokelainen P T
Krohn K
Prince A M
Finlayson N D
References (9)
9 references, click to expand
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  7. Permanganate; a new fixative for electron microscopy.
    J Biophys Biochem Cytol. 1956 Nov 25;2(6):799-802 PMID: 13398447
  8. Preferential staining of nucleic acid-containing structures for electron microscopy.
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1970-11-00
Pages
685-9
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC376174
Subset
IM
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