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PMID: 409998 Published · ppublish English Comparative Study Journal Article

Nucleotide sequence relationships between vertebrate 5.8 S ribosomal RNAs.

Nucleic acids research ·Vol. 4 ·No. 7 ·1977-07-00 ·Pages 2495-505

Khan MS, Maden BE

Abstract

Nucleotide sequences of the 5.8 S ribosomal RNAs from HeLa cells, Xenopus laevis and chick embryo fibroblasts were compared. Xenopus laevis 5.8 S RNA differs from that of HeLa cells in four internal positions and at the 3' end of the molecule. Chick 5.8 S RNA differs from that of HeLa cells in two positions. Six out of the seven interspecies differences are due to base substitutions. The other difference is due to the presence of an extra nucleotide, internally located, within the Xenopus 5.8 S sequence.

MeSH Terms
Animals Base Sequence Cell Line Chick Embryo Fibroblasts/analysis HeLa Cells/analysis Molecular Weight Nucleic Acid Conformation Oligoribonucleotides/analysis RNA, Ribosomal Ribonuclease T1 Species Specificity Xenopus
Chemicals
Oligoribonucleotides RNA, Ribosomal Ribonuclease T1
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Khan M S
Maden B E
References (15)
15 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
Published
1977-07-00
Pages
2495-505
Language
English
Region
England
NLM ID
0411011
PMCID
PMC342582
Subset
IM
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