Stability of penicillinase plasmids in Staphylococcus aureus.

Journal of bacteriology ·Vol. 107 ·No. 1 ·1971-07-00 ·Pages 68-73

Johnston LH, Dyke KG

Abstract

The isolation of mutants of Staphylococcus aureus that are affected in the stability of penicillinase plasmids is described. One mutation is plasmid borne and results in nonreplication of the plasmid at 42 C. A second type of mutation is host-borne and gives rise to instability of both mcr(I) and mcr(II) penicillinase plasmids but not a tetracycline-resistant plasmid.

MeSH Terms

Chromosomes, Bacterial Coliphages Culture Media DNA, Bacterial Drug Resistance, Microbial Genes Genetic Complementation Test Genetics, Microbial Hot Temperature Mutagens Mutation Penicillinase/biosynthesis Spectrophotometry Staining and Labeling Staphylococcus/drug effects,enzymology,growth & development,isolation & purification Sulfonic Acids Tetracycline/pharmacology Transduction, Genetic

Chemicals

Culture Media DNA, Bacterial Mutagens Sulfonic Acids Penicillinase Tetracycline

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Johnston L H

Dyke K G

References (13)

13 references, click to expand

Penicillinase production and intrinsic resistance to penicillins in Staphylococcus aures.
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Loss of antibiotic resistance in Staphylococcus aureus resulting from growth at high temperature.
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Occurrence of various types of penicillinase plasmid among 'hospital' staphylococci.
J Clin Pathol. 1967 Jan;20(1):75-9 PMID: 6016889
Chromosomal location of the genetic elements controlling penicillinase production in a strain of Staphylococcus aureus.
Nature. 1966 May 21;210(5038):804-6 PMID: 4225124
Penicillinase plasmids of Staphylococcus aureus.
Fed Proc. 1967 Jan-Feb;26(1):29-38 PMID: 4225241
Plasmid-linked resistance to inorganic salts in Staphylococcus aureus.
J Bacteriol. 1968 Apr;95(4):1335-42 PMID: 5646621
Naturally occurring penicillinase plasmids in Staphylococcus aureus.
J Bacteriol. 1969 Apr;98(1):215-21 PMID: 5781577
Thermosensitive mutants of E. coli affected in the processes of DNA synthesis and cellular division.
Cold Spring Harb Symp Quant Biol. 1968;33:677-93 PMID: 4892005
The genetics of penicillinase production in Staphylococcus aureus strain PS80.
J Gen Microbiol. 1969 Dec;59(3):289-301 PMID: 5374017
ANALYSIS BY TRANSDUCTION OF MUTATIONS AFFECTING PENICILLINASE FORMATION IN STAPHYLOCOCCUS AUREUS.
J Gen Microbiol. 1963 Oct;33:121-36 PMID: 14072829
CO-TRANSDUCTION BY A STAPHYLOCOCCAL PHAGE OF THE GENES RESPONSIBLE FOR PENICILLINASE SYNTHESIS AND RESISTANCE TO MERCURY SALTS.
Nature. 1964 Jun 27;202:1360-1 PMID: 14210993
ELIMINATION OF DRUG RESISTANCE OF STAPHYLOCOCCUS AUREUS BY TREATMENT WITH ACRIFLAVINE.
J Bacteriol. 1963 Jul;86:162-4 PMID: 14051810
NATURE AND INTERACTIONS OF THE GENETIC ELEMENTS GOVERNING PENICILLINASE SYNTHESIS IN STAPHYLOCOCCUS AUREUS.
J Bacteriol. 1965 Aug;90:467-80 PMID: 14329463

Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.107.1.68-73.1971

Published

1971-07-00

Pages

68-73

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC246886

Subset

External Links

PubMed source DOI: 10.1128/jb.107.1.68-73.1971 PMC Full Text View journal details

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Stability of penicillinase plasmids in Staphylococcus aureus.

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