Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. II. Effects of actinomycin D and cycloheximide on induction processes by phenobarbital or polycyclic hydrocarbons.

Animals Benz(a)Anthracenes/pharmacology Benzopyrenes Carbon Isotopes Cell Nucleolus/drug effects,metabolism Cells, Cultured Cycloheximide/pharmacology Dactinomycin/pharmacology Drug Antagonism Enzyme Induction Fetus Half-Life Kinetics Liver/drug effects,enzymology Metabolism/drug effects Mixed Function Oxygenases/biosynthesis,metabolism Phenobarbital/antagonists & inhibitors,pharmacology Polycyclic Compounds Proteins/metabolism RNA, Ribosomal/biosynthesis Rats Tritium Uridine/metabolism

Benz(a)Anthracenes Benzopyrenes Carbon Isotopes Polycyclic Compounds Proteins RNA, Ribosomal Tritium Dactinomycin Cycloheximide Mixed Function Oxygenases Uridine Phenobarbital