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PMID: 4112563 Published · ppublish English Journal Article

Immunochemical studies on blood groups. LIV. Classification of anti-I and anti-i sera into groups based on reactivity patterns with various antigens related to the blood group A,B,H, Le a, Le b and precursor substances.

The Journal of experimental medicine ·Vol. 135 ·No. 6 ·1972-06-01 ·Pages 1247-58

Feizi T, Kabat EA

Abstract

Quantitative precipitin assays were carried out with eleven anti-I and five anti-i cold agglutinin sera. Their reaction patterns with precursor substances and with certain antigens related to the A, B, H, Le(a), and Le(b) substances revealed at least six types of I and four types of i specificity. All of the I and i determinants appear to be represented in varying amounts on that fraction of the ovarian cyst precursor substance OG which was precipitated by 20% ethanol (OG 20% 2X). Only some of these determinants can be detected in the first periodate oxidation stages of A, B, and H substances, in cow substances, and in hydatid cyst fluid.

MeSH Terms
ABO Blood-Group System Anemia, Hemolytic/immunology Antibodies/analysis Antibody Specificity Blood Group Antigens Echinococcosis/immunology Epitopes/antagonists & inhibitors Female Humans Immune Sera/classification Immunochemistry Lewis Blood Group Antigens Milk, Human/immunology Mycoplasma Infections/immunology Oligosaccharides Ovarian Cysts/immunology Precipitin Tests
Chemicals
ABO Blood-Group System Antibodies Blood Group Antigens Epitopes Immune Sera Lewis Blood Group Antigens Oligosaccharides
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Feizi T
Kabat E A
References (16)
16 references, click to expand
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Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.135.6.1247
Published
1972-06-01
Pages
1247-58
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2139175
Subset
IM
External Links
PubMed source DOI: 10.1084/jem.135.6.1247 PMC Full Text View journal details
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