Reverse transcriptase activity of human acute leukaemic cells: purification of the enzyme, response to AMV 70S RNA, and characterization of the DNA product.

Nature: New biology ·Vol. 240 ·No. 98 ·1972-11-15 ·Pages 67-72

Sarngadharan MG, Sarin PS, Reitz MS, Gallo RC

Abstract

暂无摘要

MeSH Terms

Adenosine Triphosphate/metabolism Avian Leukosis Virus Centrifugation, Density Gradient Chromatography Chromatography, DEAE-Cellulose Chromatography, Gel Cytosine Nucleotides/metabolism DNA, Neoplasm/isolation & purification DNA, Viral/analysis,isolation & purification Guanosine Triphosphate/metabolism Humans Leukemia, Lymphoid/enzymology Nucleic Acid Hybridization Oligonucleotides/metabolism Polynucleotides/metabolism RNA, Viral/metabolism RNA-Directed DNA Polymerase/isolation & purification,metabolism Ribonucleases/metabolism Templates, Genetic Thymine Nucleotides/metabolism Tritium

Chemicals

Cytosine Nucleotides DNA, Neoplasm DNA, Viral Oligonucleotides Polynucleotides RNA, Viral Thymine Nucleotides Tritium Guanosine Triphosphate Adenosine Triphosphate RNA-Directed DNA Polymerase Ribonucleases

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Sarngadharan M G

Sarin P S

Reitz M S

Gallo R C

Article Info

Journal

Nature: New biology

Abbr.

Nat New Biol

ISSN

0090-0028

DOI

10.1038/newbio240067a0

Published

1972-11-15

Pages

67-72

Language

English

Region

England

NLM ID

0410463

Subset

External Links

PubMed source DOI: 10.1038/newbio240067a0

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Reverse transcriptase activity of human acute leukaemic cells: purification of the enzyme, response to AMV 70S RNA, and characterization of the DNA product.

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