Structural proteins of mammalian oncogenic RNA viruses: murine leukemia virus neutralization by antisera prepared against purified envelope glycoprotein.

Journal of virology ·Vol. 14 ·No. 1 ·1974-07-00 ·Pages 187-9

Steeves RA, Strand M, August JT

Abstract

Goat and rabbit antisera prepared against a purified Rauscher murine leukemia virus glycoprotein (gp69/71) rapidly neutralized spleen focus-forming virus in Rauscher and Friend virus preparations. Absorption studies revealed that most of the neutralizing activity of goat anti-Rauscher virus gp69/71 serum was directed against type- and group-specific determinants.

MeSH Terms

AKR murine leukemia virus/immunology Animals Epitopes Friend murine leukemia virus/immunology Gammaretrovirus/immunology Glycoproteins Goats/immunology Hemagglutinins, Viral Immune Sera Leukemia Virus, Feline/immunology Neutralization Tests Rabbits/immunology Rauscher Virus/immunology

Chemicals

Epitopes Glycoproteins Hemagglutinins, Viral Immune Sera

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Steeves R A

Strand M

August J T

References (5)

5 references, click to expand

Neutralization kinetics of friend and Rauscher leukemia viruses studied with the spleen focus assay method.
Int J Cancer. 1967 May 15;2(3):235-44 PMID: 6041991
Isolation and characterization of a lymphatic leukemia virus in the Friend virus complex.
J Natl Cancer Inst. 1971 Jun;46(6):1209-17 PMID: 4325930
A classification of the murine leukemia viruses. Neutralization of pseudotypes of Friend spleen focus-forming virus by type-specific murine antisera.
J Exp Med. 1972 Oct 1;136(4):832-50 PMID: 4341440
Structural proteins of oncogenic ribonucleic acid viruses. Interspec II, a new interspecies antigen.
J Biol Chem. 1973 Aug 25;248(16):5627-33 PMID: 4124987
Structural proteins of mammalian oncogenic RNA viruses: multiple antigenic determinants of the major internal protein and envelope glycoprotein.
J Virol. 1974 Jan;13(1):171-80 PMID: 4129838

Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.14.1.187-189.1974

Published

1974-07-00

Pages

187-9

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC355496

Subset

External Links

PubMed source DOI: 10.1128/JVI.14.1.187-189.1974 PMC Full Text View journal details

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Structural proteins of mammalian oncogenic RNA viruses: murine leukemia virus neutralization by antisera prepared against purified envelope glycoprotein.

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