Real-time generation of renal artery hemodynamic parameters using a point cloud-based deep learning model.

Renal artery stenosis (RAS) is a major cause of secondary hypertension, requiring accurate hemodynamic evaluation for clinical intervention. This study presents a deep learning framework integrating Mamba-based state-space modeling (SSM) with hierarchical point cloud processing for real-time hemodynamic prediction. A computational dataset was generated from three-dimensional renal artery models using Bessel-curve reconstruction and computational fluid dynamics (CFD) simulations. By combining PointNet++ with Mamba's selective mechanisms, the model effectively captures hemodynamic metrics while preserving local vascular features. The method provides real-time renal hemodynamic predictions with computational efficiency improved by several orders of magnitude while preserving accuracy comparable to CFD.