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PMID: 4141683 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Cytological detection of the c-25H deletion involving the albino (c) locus on chromosome 7 in the mouse.

Genetics ·Vol. 78 ·No. 3 ·1974-11-00 ·Pages 905-10

Miller DA, Dev VG, Tantravahi R, Miller OJ, Schiffman MB, Yates RA, Gluecksohn-Waelsch S

Abstract

A deletion of the albino (c) locus on mouse chromosome 7 has been demonstrated using Q- and G-banding methods in a mouse heterozygous for the radiation-induced lethal albino allele, c(25H). The deletion, which is thought to be 1-6 cM long, represents about 7.6% of the length of the metaphase chromosome.

MeSH Terms
Albinism/genetics Alleles Animals Cell Division Chromatids/ultrastructure Chromosome Aberrations Chromosome Mapping Chromosomes/radiation effects,ultrastructure Female Genes, Lethal Genetic Complementation Test Heterozygote Karyotyping Male Mice Mice, Inbred AKR Mutation Radiation Genetics Staining and Labeling
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Miller D A
Dev V G
Tantravahi R
Miller O J
Schiffman M B
Yates R A
Gluecksohn-Waelsch S
References (10)
10 references, click to expand
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
Published
1974-11-00
Pages
905-10
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1224563
Subset
IM
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