Relationship between antihistamic activity and plasma level of diphenhydramine.

European journal of clinical pharmacology ·Vol. 7 ·No. 5 ·1974-08-23 ·Pages 393-5

Bilzer W, Gundert-Remy U, Weber E

Abstract

暂无摘要

MeSH Terms

Administration, Oral Adult Capsules Chromatography, Gas Diphenhydramine/administration & dosage,blood,therapeutic use Histamine/administration & dosage Histamine H1 Antagonists/administration & dosage,blood,therapeutic use Humans Hypnotics and Sedatives/pharmacology Injections, Intradermal Kinetics Male Pharmaceutical Vehicles Problem Solving Psychometrics Skin Tests Tablets, Enteric-Coated Time Factors Time Perception/drug effects

Chemicals

Capsules Histamine H1 Antagonists Hypnotics and Sedatives Pharmaceutical Vehicles Tablets, Enteric-Coated Histamine Diphenhydramine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Bilzer W

Gundert-Remy U

Weber E

References (6)

6 references, click to expand

Blood levels of pentobarbital sodium, meprobamate, and tybamate in relation to clinical effects.
Clin Pharmacol Ther. 1968 Mar-Apr;9(2):204-8 PMID: 4867871
Identification of diphenhydramine urinary metabolites in the rhesus monkey.
Biochem Pharmacol. 1968 Oct;17(10):2125-36 PMID: 4972258
Ethyl alcohol: blood levels and performance decrements after oral administration to man.
Psychopharmacologia. 1971;19(3):246-61 PMID: 5565241
The quantitative comparison of histamine antagonists in man.
Proc R Soc Med. 1949 Aug;42(8):615-23 PMID: 18138763
Determination of nanogram quantities of diphenhydramine and orphenadrine in human plasma using gas-liquid chromatography.
Eur J Clin Pharmacol. 1973 Dec;6(4):268-70 PMID: 4777260
Species differences in the metabolism of diphenhydramine (Benadryl).
Proc Soc Exp Biol Med. 1970 Dec;135(3):849-53 PMID: 4992081

Article Info

Journal

European journal of clinical pharmacology

Abbr.

Eur J Clin Pharmacol

ISSN

0031-6970

DOI

10.1007/BF00558213

Published

1974-08-23

Pages

393-5

Language

English

Region

Germany

NLM ID

1256165

Subset

External Links

PubMed source DOI: 10.1007/BF00558213 View journal details

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Relationship between antihistamic activity and plasma level of diphenhydramine.

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