Lymphoid cells producing antibody against simple haptens: detection and enumeration.

Science (New York, N.Y.) ·Vol. 152 ·No. 3727 ·1966-06-03 ·Pages 1378-9

Merchant B, Hraba T

Abstract

Enumeration of cells producing antibody against arsanilic acid was made feasible by the use of hapten-conjugated sheep erythrocytes for the localized hemolysis-in-gel technique. The time of appearance and numbers of these hapten-specific plaque-forming cells correlated closely with the development of arsanilic acid-specific serum antibodies.

MeSH Terms

Adjuvants, Immunologic Animals Antibody Formation Arsenic Blood Proteins Erythrocytes Guinea Pigs Haptens Hemocyanins Hemolysis In Vitro Techniques Lymphoid Tissue/cytology Mycobacterium tuberculosis Rabbits Spleen/cytology gamma-Globulins

Chemicals

Adjuvants, Immunologic Blood Proteins Haptens gamma-Globulins Hemocyanins Arsenic

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Merchant B

Hraba T

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.152.3727.1378

Published

1966-06-03

Pages

1378-9

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.152.3727.1378 View journal details

Analysis Services

Lymphoid cells producing antibody against simple haptens: detection and enumeration.

Contact

WeChat Official Account