Renal failure and interstitial nephritis due to penicillin and methicillin.

Acute Kidney Injury/chemically induced,immunology Adult Aged Animals Blood Urea Nitrogen Drug Hypersensitivity Endocarditis, Bacterial/drug therapy Eosinophils Female Fluorescent Antibody Technique Goats Haptens Humans Immune Sera Kidney/pathology Kidney Glomerulus/pathology Kidney Tubules/pathology Leukocytes Male Methicillin/administration & dosage,adverse effects Middle Aged Nephritis, Interstitial/chemically induced,immunology Osteomyelitis/drug therapy Penicillins/administration & dosage,adverse effects Rabbits Sepsis/drug therapy Staphylococcal Infections/drug therapy gamma-Globulins

Haptens Immune Sera Penicillins gamma-Globulins Methicillin