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PMID: 4206459 Published · ppublish English Journal Article

A new mutant controlling mitotic chromosome disjunction in Drosophila melanogaster.

Genetics ·Vol. 76 ·No. 1 ·1974-01-00 ·Pages 51-63

Gelbart WM

Abstract

A new mutant, mit (mitotic loss inducer), is described. The mutant is recessive and maternal in action, producing gynandromorphs and haplo-4 mosaics among the progeny of homozygous mit females. Mosaic loss of maternal or paternal chromosomes can occur. The probabilities of either maternal or paternal X chromosome loss are equal. mit has been mapped to approximately 57 on the standard X chromosome map.-Using gyandromorphs generated by mit, a morphogenetic fate map, placing the origins of 40 cuticular structures on the blastoderm surface, has been constructed. This fate map is consistent with embryological data and with the two other fate maps generated in different ways.

MeSH Terms
Animals Chromosome Mapping Chromosomes Crosses, Genetic Drosophila melanogaster Female Gene Frequency Genes, Recessive Genotype Heterozygote Homozygote Male Mathematics Meiosis Mitosis Models, Biological Mutation Sex Chromosomes
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Gelbart W M
References (4)
4 references, click to expand
  1. Cell lineage of the imaginal discs in Drosophila gynandromorphs.
    J Exp Zool. 1969 Jan;170(1):61-75 PMID: 5780530
  2. Chromosome segregation influenced by two alleles of the meiotic mutant c(3)G in Drosophila melanogaster.
    Genetics. 1972 Jul;71(3):367-400 PMID: 4624918
  3. [Roentgen mosaic spots & defective mutations at the eye of Drosophila & the evolutive physiology of the eye].
    Z Indukt Abstamm Vererbungsl. 1957;88(3):333-73 PMID: 13496909
  4. An Induced Maternal Effect on the Stability of the Ring-X-Chromosome of Drosophila Melanogaster.
    Proc Natl Acad Sci U S A. 1952 Aug;38(8):687-93 PMID: 16589162
Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
Published
1974-01-00
Pages
51-63
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1213054
Subset
IM
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