Linkage studies in a large kindred with familial hypercholesterolemia.

American journal of human genetics ·Vol. 26 ·No. 5 ·1974-09-00 ·Pages 598-603

Ott J, Schrott HG, Goldstein JL, Hazzard WR, Allen FH, Falk CT, Motulsky AG

Abstract

暂无摘要

MeSH Terms

ABO Blood-Group System/analysis Acid Phosphatase/blood Alanine Transaminase/blood Aminohydrolases/blood Blood Group Antigens Blood Proteins/analysis Complement System Proteins/analysis Computers Diagnosis, Differential Erythrocytes/enzymology Female Gene Frequency Genetic Linkage Haptoglobins/analysis Humans Hypercholesterolemia/genetics Male Pedigree Phosphoglucomutase/blood Recombination, Genetic Rh-Hr Blood-Group System/analysis

Chemicals

ABO Blood-Group System Blood Group Antigens Blood Proteins Haptoglobins Rh-Hr Blood-Group System Complement System Proteins Alanine Transaminase Acid Phosphatase Aminohydrolases Phosphoglucomutase

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Ott J

Schrott H G

Goldstein J L

Hazzard W R

Allen F H

Falk C T

Motulsky A G

References (9)

9 references, click to expand

Fat transport in lipoproteins--an integrated approach to mechanisms and disorders.
N Engl J Med. 1967 Jan 19;276(3):148-56 contd PMID: 5334266
Segregation and linkage analyses of twelve blood and serum group systems.
Hum Hered. 1969;19(4):419-32 PMID: 4189227
Familial hypercholesterolemia in a large indred. Evidence for a monogenic mechanism.
Ann Intern Med. 1972 May;76(5):711-20 PMID: 5025321
Failure to demonstrate linkage between the loci for the Rh and Duffy blood groups.
Ann Hum Genet. 1973 Jan;36(3):353-4 PMID: 4714425
Hyperlipidemia in coronary heart disease. I. Lipid levels in 500 survivors of myocardial infarction.
J Clin Invest. 1973 Jul;52(7):1533-43 PMID: 4718952
Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia.
J Clin Invest. 1973 Jul;52(7):1544-68 PMID: 4718953
Hyperlipidemia in coronary heart disease. 3. Evaluation of lipoprotein phenotypes of 156 genetically defined survivors of myocardial infarction.
J Clin Invest. 1973 Jul;52(7):1569-77 PMID: 4352458
Linkage data on Rh, PGM1, PGD, Peptidase C and Fy from family studies.
Ann Hum Genet. 1973 Apr;36(4):393-9 PMID: 4201296
Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.
Am J Hum Genet. 1974 Sep;26(5):588-97 PMID: 4422075

Article Info

Journal

American journal of human genetics

Abbr.

Am J Hum Genet

ISSN

0002-9297

Published

1974-09-00

Pages

598-603

Language

English

Region

United States

NLM ID

0370475

PMCID

PMC1762725

Subset

External Links

PubMed source PMC Full Text View journal details

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Linkage studies in a large kindred with familial hypercholesterolemia.

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