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PMID: 4217104 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Serologically active glycolipid families from Mycobacterium bovis BCG. II. Serologic studies on human sera.

American journal of epidemiology ·Vol. 100 ·No. 6 ·1974-12-00 ·Pages 477-86

Reggiardo Z, Middlebrook G

Abstract

Serological tests with serologically active glycolipids from Mycobacterium bovis BCG were investigated for their possible use in the diagonis of mycobacterioses. The results were positive with 95 percent of sera from patients with far advanced and moderately advanced tuberculosis, 80 percent of sera from patients with newly diagnosed tuberculosis and 75 percent of patients with atypical mycobacterial diseases. "False" positive serologic reactions were obtained from 4 percent or less. Furthermore, 39 percent of sera from recent tuberculin converters were positive compared with only 9 percent of sera from unselected PPD positive individuals.

MeSH Terms
Antibodies, Bacterial/analysis Antibody Formation Chagas Disease/immunology Coombs Test False Positive Reactions Glycolipids/immunology Hemagglutination Inhibition Tests Hemagglutination Tests Histoplasmosis/immunology Humans Leprosy/immunology Malaria/immunology Mycobacterium Infections/immunology Mycobacterium bovis/immunology Mycoplasma Infections/immunology Syphilis/immunology Tuberculosis/immunology
Chemicals
Antibodies, Bacterial Glycolipids
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Reggiardo Z
Middlebrook G
Article Info
Journal
American journal of epidemiology
Abbr.
Am J Epidemiol
ISSN
0002-9262
Published
1974-12-00
Pages
477-86
Language
English
Region
United States
NLM ID
7910653
Subset
IM
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