Morphological alterations of Pseudomonas aeruginosa by ticarcillin: a scanning electron microscope study.

Antimicrobial agents and chemotherapy ·Vol. 6 ·No. 6 ·1974-12-00 ·Pages 853-5

Prior RB, Warner JF

Abstract

Pseudomonas aeruginosa was exposed to 0.1, 1.0, 10, 100, and 1,000 times the minimal inhibitory concentration of ticarcillin in vitro and subsequently examined with the scanning electron microscope. The morphological alterations observed were filamentation, mid-cell defects, and spheroplast formation, and these alterations were dependent upon the drug concentration.

MeSH Terms

Carboxylic Acids/pharmacology Culture Media Microscopy, Electron, Scanning Penicillins/analogs & derivatives Pseudomonas aeruginosa/drug effects,ultrastructure Thiophenes/pharmacology

Chemicals

Carboxylic Acids Culture Media Penicillins Thiophenes

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Prior R B

Warner J F

References (3)

3 references, click to expand

In vitro studies of alpha-carboxyl-3-thienylmethyl penicillin, a new semisynthetic penicillin.
Appl Microbiol. 1971 Jan;21(1):61-5 PMID: 4924999
Fluid and pharmacological dynamics in a subcutaneous chamber implanted in rats.
Antimicrob Agents Chemother. 1973 Aug;4(2):196-7 PMID: 4790940
Artifacts induced by preparation for scanning electron microscopy, in Proteus mirabilis exposed to carbenicillin.
Can J Microbiol. 1974 May;20(5):794-5 PMID: 4598868

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.6.6.853

Published

1974-12-00

Pages

853-5

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC444749

Subset

External Links

PubMed source DOI: 10.1128/AAC.6.6.853 PMC Full Text View journal details

Analysis Services

Morphological alterations of Pseudomonas aeruginosa by ticarcillin: a scanning electron microscope study.

Contact

WeChat Official Account