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PMID: 4230391 Published · ppublish English Journal Article

Increase of dihydrofolate reductase activity in cultured mammalian cells after exposure to methotrexate.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 58 ·No. 4 ·1967-10-00 ·Pages 1632-7

Hillcoat BL, Swett V, Bertino JR

Abstract

暂无摘要

MeSH Terms
Culture Techniques Cycloheximide/pharmacology Dactinomycin/pharmacology Floxuridine/pharmacology Humans Leucine/metabolism Leukemia, Myeloid/enzymology Lymphocytes/drug effects,enzymology Methotrexate/pharmacology Neoplasm Proteins/biosynthesis Nucleosides/metabolism Puromycin/pharmacology RNA, Neoplasm/biosynthesis Tetrahydrofolate Dehydrogenase/metabolism Tritium
Chemicals
Neoplasm Proteins Nucleosides RNA, Neoplasm Floxuridine Tritium Dactinomycin Puromycin Cycloheximide Tetrahydrofolate Dehydrogenase Leucine Methotrexate
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hillcoat B L
Swett V
Bertino J R
References (14)
14 references, click to expand
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    J Biol Chem. 1964 Feb;239:479-85 PMID: 14169148
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  13. COMPARATIVE BIOCHEMISTRY OF BACTERIAL AND PHAGE-INDUCED DIHYDROFOLATE REDUCTASES.
    J Biol Chem. 1965 May;240:2142-7 PMID: 14299639
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.58.4.1632
Published
1967-10-00
Pages
1632-7
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC223971
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.58.4.1632 PMC Full Text View journal details
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