Activation of human plasminogen by an insoluble derivative of urokinase. Structural changes of plasminogen in the course of activation to plasmin and demonstration of a possible intermediate compound.

Amino Acids/analysis Autoanalysis Autolysis Benzoates Chromatography, Affinity Disulfides Electrophoresis, Polyacrylamide Gel Enzyme Activation Fibrinolysin/analysis,antagonists & inhibitors,metabolism Fibrinolytic Agents/metabolism Guanidines Humans Macromolecular Substances Methionine/analysis Molecular Weight Nitrophenols Peptides/analysis Plasminogen/analysis,metabolism Valine/analysis

Amino Acids Benzoates Disulfides Fibrinolytic Agents Guanidines Macromolecular Substances Nitrophenols Peptides Plasminogen Methionine Fibrinolysin Valine