Inhibition of pinocytosis by cytochalasin B. Decrease in intracellular lysosomal-enzyme activities and increased storage of glycosaminoglycans.

Cells, Cultured Cytochalasin B/pharmacology Fibroblasts/drug effects,metabolism Glucuronidase/metabolism Glycosaminoglycans/metabolism Hexosaminidases/metabolism Humans Intellectual Disability/metabolism Lysosomes/drug effects,enzymology Mucopolysaccharidoses/metabolism Pinocytosis/drug effects Skin Sulfates Syndrome

Glycosaminoglycans Sulfates Cytochalasin B Hexosaminidases Glucuronidase