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PMID: 4297941 Published · ppublish English Journal Article

The distribution of monoamine oxidase and alpha-glycerophosphate dehydrogenase in pig brain.

The Biochemical journal ·Vol. 108 ·No. 1 ·1968-06-00 ·Pages 95-9

Tipton KF, Dawson AP

Abstract

Activities of the enzymes monoamine oxidase (EC 1.4.3.4), alpha-glycerophosphate dehydrogenase (EC 1.1.99.5) and cytochrome oxidase (EC 1.9.3.1) were determined in homogenates and in the mitochondrial fraction prepared from individual regions of pig brain. The variation in the activity of alpha-glycerophosphate dehydrogenase paralleled that of cytochrome oxidase, but this was not the case with monoamine oxidase. The differences in the activities of the enzymes among homogenates of the various regions of the brain persisted in mitochondria prepared from these homogenates. The purification of these three enzymes paralleled each other when mitochondria were prepared, suggesting that the three enzymes are bound to the same particles.

MeSH Terms
Animals Brain/anatomy & histology,enzymology Cerebellum/enzymology Corpus Callosum/enzymology Electron Transport Complex IV/analysis Frontal Lobe/enzymology Glycerolphosphate Dehydrogenase/analysis Hypothalamus/enzymology Manometry Medulla Oblongata/enzymology Mitochondria/enzymology Monoamine Oxidase/analysis Oxygen Consumption Pons/enzymology Swine Thalamus/enzymology
Chemicals
Glycerolphosphate Dehydrogenase Monoamine Oxidase Electron Transport Complex IV
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Tipton K F
Dawson A P
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23 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj1080095
Published
1968-06-00
Pages
95-9
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1198773
Subset
IM
External Links
PubMed source DOI: 10.1042/bj1080095 PMC Full Text View journal details
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