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PMID: 4301316 Published · ppublish English Journal Article

Electron microscopy of herpes simplex virus. I. Entry.

Journal of virology ·Vol. 2 ·No. 5 ·1968-05-00 ·Pages 507-16

Morgan C, Rose HM, Mednis B

Abstract

Although capsids of herpes simplex virus were encountered within phagocytic vesicles, they were more commonly observed free within the cytoplasm. Stages in the release of virus from vesicles were not seen. There appeared to be five distinct steps in the process whereby the virus initiates infection: attachment, digestion of the viral envelope, digestion of the cell wall, passage of the capsid directly into the cytoplasm, and digestion of the capsid with release of the core. Antibody probably interferes with the first two stages.

MeSH Terms
Cytoplasm Female HeLa Cells Herpes Simplex/etiology Humans Microscopy, Electron Phagocytosis Simplexvirus Viral Proteins
Chemicals
Viral Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Morgan C
Rose H M
Mednis B
References (28)
28 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.2.5.507-516.1968
Published
1968-05-00
Pages
507-16
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC375640
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.2.5.507-516.1968 PMC Full Text View journal details
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