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PMID: 4309629 Published · ppublish English Journal Article

Axonal transport of proteins in experimental neuropathies.

Science (New York, N.Y.) ·Vol. 166 ·No. 3904 ·1969-10-24 ·Pages 524-5

Pleasure DE, Mishler KC, Engel WK

Abstract

Axoplasmic flow of proteins is interrlupted in cats with neuropatlhy induced by acrylamide, but it is niot initerrupted in nzormlal cats and in those with neuropathy induced by tri-orthocresyl phiospliate. The proteins move from lumbosacral motor neurons along the ventral roots and from ganglion cells toward the spinal cord along the dorsal roots at about 1(1/2) millimeters per day.

MeSH Terms
Acrylates Amides Animals Autoradiography Axons/physiology Cats Injections, Intraperitoneal Leucine/metabolism Nervous System Diseases/chemically induced,metabolism Proteins/metabolism Synaptic Transmission Tritium
Chemicals
Acrylates Amides Proteins Tritium Leucine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Pleasure D E
Mishler K C
Engel W K
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1969-10-24
Pages
524-5
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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