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PMID: 4311727 Published · ppublish English Journal Article

Latent cytomegalovirus infection in blood donors.

British medical journal ·Vol. 4 ·No. 5684 ·1969-12-13 ·Pages 660-2

Diosi P, Moldovan E, Tomescu N

Abstract

Twenty-one out of 32 apparently healthy blood donors aged 21 to 65 years yielded positive complement fixation tests with a cytomegalovirus antigen, at titres ranging from 1:8 to 1:64. Virus was present in leucocyte cultures of fresh peripheral blood of two seropositive subjects from a total of 35 donors examined. Plasma and 48-hour stored blood specimens failed to disclose virus in culture. Viruria could not be demonstrated, and there was no evidence of recent illness in the study group. These findings suggest that subclinical viraemia is not uncommon in blood donors.

MeSH Terms
Adult Aged Blood/microbiology Blood Donors Carrier State Complement Fixation Tests Culture Techniques Cytomegalovirus/isolation & purification Herpesviridae Infections/diagnosis,epidemiology Humans Leukocytes/microbiology Middle Aged Plasma/microbiology Urine/microbiology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Diosi P
Moldovan E
Tomescu N
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30 references, click to expand
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Article Info
Journal
British medical journal
Abbr.
Br Med J
ISSN
0007-1447
DOI
10.1136/bmj.4.5684.660
Published
1969-12-13
Pages
660-2
Language
English
Region
England
NLM ID
0372673
PMCID
PMC1630231
Subset
IM
External Links
PubMed source DOI: 10.1136/bmj.4.5684.660 PMC Full Text
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