Overgrowth stimulating factor released from Rous sarcoma cells.

Science (New York, N.Y.) ·Vol. 167 ·No. 3922 ·1970-02-27 ·Pages 1271-2

Rubin H

Abstract

An assay is described for a nonzviral factor from the medium of Rous sarcoma cells which stimulates rapid and sustained cellular overgrawth in crowded chick embryo cultures. The factor is nondialyzable and thermnolabile and is released in large amounts several days after the first visible transformation of newly infected chick embryo cells.

MeSH Terms

Animals Chick Embryo/cytology Culture Media Culture Techniques DNA/biosynthesis Mitosis Sarcoma, Avian Stimulation, Chemical Thymidine/metabolism Tritium

Chemicals

Culture Media Tritium DNA Thymidine

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Rubin H

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.167.3922.1271

Published

1970-02-27

Pages

1271-2

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.167.3922.1271 View journal details

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