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PMID: 4317924 Published · ppublish English Journal Article

Tilorone hydrochloride: mode of action.

Science (New York, N.Y.) ·Vol. 169 ·No. 3951 ·1970-09-18 ·Pages 1214-5

Mayer GD, Krueger RF

Abstract

An antiviral serum component is found in mice treated orally with tilorone hydrochloride. The active material fulfills sufficient biological criteria to be classified as an interferon.

MeSH Terms
Administration, Oral Animals Antiviral Agents/administration & dosage,pharmacology Blood Carcinoma Cell Line Dactinomycin/pharmacology Dialysis Encephalomyocarditis virus/drug effects Fluorenes/administration & dosage,pharmacology Laryngeal Neoplasms Mice Ribonucleases Trypsin Vesicular stomatitis Indiana virus/drug effects
Chemicals
Antiviral Agents Fluorenes Dactinomycin Ribonucleases Trypsin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Mayer G D
Krueger R F
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.169.3951.1214
Published
1970-09-18
Pages
1214-5
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.169.3951.1214 View journal details
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