Focus formation by a murine sarcoma leukemia virus complex. II. Quantitative aspects of the interaction between radiation leukemia virus and its murine sarcoma virus pseudotype in strain C57BL mouse embryo cells.

Journal of virology ·Vol. 5 ·No. 4 ·1970-04-00 ·Pages 437-45

Declève A, Lieberman M, Hahn GM, Kaplan HS

Abstract

A quantitative study has been made of the interactions between radiation leukemia virus (RadLV), its murine sarcoma virus pseudotype, and their C57BL host cells. The elimination of interference phenomena by delayed infection of cells with RadLV made possible the quantitative determination of the pseudotype in terms of defective sarcoma and endogenous RadLV particles. This in turn permitted the quantitative assessment of RadLV helper activity and of the various factors which influence the accuracy and sensitivity of the helper assay.

MeSH Terms

Animals Culture Techniques Fibroblasts Gammaretrovirus/growth & development,pathogenicity Leukemia Virus, Murine/growth & development,pathogenicity Mathematics Mice Ultracentrifugation Viral Interference Virus Cultivation

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Declève A

Lieberman M

Hahn G M

Kaplan H S

References (11)

11 references, click to expand

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Proc Natl Acad Sci U S A. 1966 Apr;55(4):780-6 PMID: 5219685
A virus-induced rhabdomyosarcoma of mice.
Natl Cancer Inst Monogr. 1966 Sep;22:139-42 PMID: 4288557
Titration patterns of a murine sarcoma-leukemia virus complex: evidence for existence of competent sarcoma virions.
Science. 1968 Jan 19;159(3812):325-9 PMID: 4294341
Radiation leukemia virus: quantitative tissue culture assay.
Science. 1969 Jul 18;165(3890):306-9 PMID: 4306917
Antigenic characteristics of lymphomas induced by radiation leukemia virus (RadLV) in mice and rats.
Cancer Res. 1968 Dec;28(12):2522-8 PMID: 4302535
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Science. 1959 Aug 14;130(3372):387-8 PMID: 13675761
Rescue of the defective murine sarcoma virus genome by radiation-induced leukemia virus from C57BL mice.
Proc Natl Acad Sci U S A. 1967 Nov;58(5):1870-7 PMID: 4295580
Rescue of the defective genome of Moloney sarcoma virus from a noninfectious hamster tumor and the production of pseudotype sarcoma viruses with various murine leukemia viruses.
Proc Natl Acad Sci U S A. 1966 Oct;56(4):1164-9 PMID: 5230142
AN UNIDENTIFIED VIRUS WHICH CAUSES THE RAPID PRODUCTION OF TUMOURS IN MICE.
Nature. 1964 Dec 12;204:1104-5 PMID: 14243400
Tissue culture assay of helper activity of murine leukemia virus for murine sarcoma virus.
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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.5.4.437-445.1970

Published

1970-04-00

Pages

437-45

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC376024

Subset

External Links

PubMed source DOI: 10.1128/JVI.5.4.437-445.1970 PMC Full Text View journal details

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Focus formation by a murine sarcoma leukemia virus complex. II. Quantitative aspects of the interaction between radiation leukemia virus and its murine sarcoma virus pseudotype in strain C57BL mouse embryo cells.

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