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PMID: 4328483 Published · ppublish English Journal Article

Latent herpes simplex virus in spinal ganglia of mice.

Science (New York, N.Y.) ·Vol. 173 ·No. 3999 ·1971-08-27 ·Pages 843-5

Stevens JG, Cook ML

Abstract

Herpes simplex virus establishes a persistent, latent infection in spinal ganglia after mice have recovered from posterior paralysis. Infectious virus is replicated when these ganglia are explanted and maintained as organ cultures in vitro.

MeSH Terms
Animals Culture Techniques Ganglia, Spinal/microbiology,pathology Herpesviridae Infections/immunology,microbiology,pathology Mice Microscopy, Electron Neutralization Tests Simplexvirus/isolation & purification Time Factors Virus Replication
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Stevens J G
Cook M L
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.173.3999.843
Published
1971-08-27
Pages
843-5
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.173.3999.843 View journal details
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