Adenyl cyclase in normal and transformed fibroblasts in tissue culture. Activation by prostaglandins.

Adenosine Triphosphate/metabolism Adenylyl Cyclases/metabolism Animals Carcinogens Cell Line/drug effects Cell Transformation, Neoplastic Cells/enzymology Clone Cells Cricetinae Culture Techniques Cyclic AMP/metabolism Embryo, Mammalian Enzyme Activation Fibroblasts/enzymology Fluorine/pharmacology Hydrogen-Ion Concentration Kidney/enzymology L Cells/enzymology Leukemia Virus, Murine Mice Phosphorus Isotopes Polyomavirus Prostaglandins/pharmacology Rats Simian virus 40 Stimulation, Chemical Time Factors Transformation, Genetic Tritium

Carcinogens Phosphorus Isotopes Prostaglandins Tritium Fluorine Adenosine Triphosphate Cyclic AMP Adenylyl Cyclases