Home LiteratureArticle Details
PMID: 4329158 Published · ppublish English Journal Article

Morphogenesis of the collagenous stroma in the chick cornea.

The Journal of cell biology ·Vol. 50 ·No. 3 ·1971-09-00 ·Pages 840-58

Trelstad RL, Coulombre AJ

Abstract

The embryonic chick corneal epithelium produces a highly structured acellular matrix beneath its basal surface during early development. This matrix, which contains collagen, serves as a morphogenetic template for subsequent stromal development in that the three-dimensional architecture of the adult corneal stroma is initially established, in miniature, in this epithelially derived connective tissue. Examination of the early corneal epithelium and matrix in both the light and electron microscope suggests that self assembly of the matrix may be one of several important factors in the morphogenesis of this early connective tissue.

MeSH Terms
Animals Autoradiography Chick Embryo Collagen Cornea/analysis,cytology,embryology Epithelial Cells Epithelium/embryology Histocytochemistry Inclusion Bodies Methods Microscopy, Electron Microtubules Morphogenesis Proline Time Factors Tritium
Chemicals
Tritium Collagen Proline
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Trelstad R L
Coulombre A J
References (21)
21 references, click to expand
  1. The behavior of collagen units as a model in morphogenesis.
    J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):261-74 PMID: 13357551
  2. Secretion of collagenous stroma by isolated epithelium grown in vitro.
    Exp Cell Res. 1971 Mar;65(1):215-20 PMID: 5549545
  3. ORIENTED MICROTUBULES IN ELONGATING CELLS OF THE DEVELOPING LENS RUDIMENT AFTER INDUCTION.
    Proc Natl Acad Sci U S A. 1964 Oct;52:1091-9 PMID: 14224388
  4. The effect of pH on the stability of purified glutaraldehyde.
    J Histochem Cytochem. 1969 Nov;17(11):756-7 PMID: 5386303
  5. The skeleton of the eye. I. Conjunctival papillae and scleral ossicles.
    Dev Biol. 1962 Dec;5:382-401 PMID: 14023393
  6. Collagen and mucopolysaccharide biosynthesis in the developing chick cornea.
    Dev Biol. 1970 Mar;21(3):292-317 PMID: 4245074
  7. Observations on the morphology of the proteinpolysaccharide complex of bovine nasal cartilage and its relationship to collagen.
    Proc R Soc Lond B Biol Sci. 1966 Oct 11;165(1001):440-9 PMID: 4380569
  8. The Golgi apparatus in chick corneal epithelium: changes in intracellular position during development.
    J Cell Biol. 1970 Apr;45(1):34-42 PMID: 4195852
  9. Glycosaminoglycans in the developing corneal stroma.
    Exp Eye Res. 1961 Dec;1:116-21 PMID: 13861727
  10. Macromolecular fabrics and patterns.
    J Cell Physiol Suppl. 1957 May;49(Suppl 1):105-12 PMID: 13449114
  11. Microtubules in the formation and development of the primary mesenchyme in Arbacia punctulata. I. The distribution of microtubules.
    J Cell Biol. 1969 Apr;41(1):201-26 PMID: 5775786
  12. Observations on the distribution of the proteinpolysaccharide complex and collagen in bovine articular cartilage.
    J Cell Sci. 1967 Mar;2(1):129-36 PMID: 4166205
  13. BIOSYNTHESIS OF COLLAGEN AND NON-COLLAGEN PROTEIN DURING DEVELOPMENT OF THE CHICK CORNEA.
    J Cell Biol. 1965 Apr;25:69-78 PMID: 14283632
  14. Observations on the collagen and proteinpolysaccharide complex of rabbit cornea stroma.
    J Cell Sci. 1969 Mar;4(2):421-36 PMID: 5804891
  15. Effects of cytochalasin B upon microfilaments involved in morphogenesis of salivary epithelium.
    Proc Natl Acad Sci U S A. 1970 Jun;66(2):360-1 PMID: 5271169
  16. CORNEAL DEVELOPMENT. 3. THE ROLE OF THE THYROID IN DEHYDRATION AND THE DEVELOPMENT OF TRANSPARENCY.
    Exp Eye Res. 1964 Jun;3:105-14 PMID: 14211912
  17. Isolation of two distinct collagens from chick cartilage.
    Biochemistry. 1970 Dec 8;9(25):4993-8 PMID: 5480162
  18. Chick cartilage collagen: a new type of alpha 1 chain not present in bone or skin of the species.
    Proc Natl Acad Sci U S A. 1969 Dec;64(4):1264-8 PMID: 5271750
  19. Collagen formation by fibroblasts of the chick embryo dermis.
    J Biophys Biochem Cytol. 1959 Jan 25;5(1):153-66 PMID: 13630947
  20. The role of intraocular pressure in the development of the chick eye. II. Control of corneal size.
    AMA Arch Ophthalmol. 1957 Feb;57(2):250-3 PMID: 13393895
  21. ELECTRON-MICROSCOPIC STUDY OF THE TEXTURE OF THE BASEMENT MEMBRANE OF LARVAL AMPHIBIAN SKIN.
    Proc Natl Acad Sci U S A. 1954 Jun;40(6):528-40 PMID: 16589519
Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.50.3.840
Published
1971-09-00
Pages
840-58
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2108295
Subset
IM
External Links
PubMed source DOI: 10.1083/jcb.50.3.840 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2