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PMID: 4331703 Published · ppublish English Journal Article

Input and output signals in a model neural system: the regulation of melatonin production in the pineal gland.

In vitro ·Vol. 6 ·No. 3 ·1970-00-00 ·Pages 197-204

Klein DC, Weller J

Abstract

暂无摘要

MeSH Terms
Animals Chemical Phenomena Chemistry Culture Media Cyclic AMP/pharmacology Indoles/pharmacology Male Melatonin/biosynthesis Methionine/pharmacology Methods Models, Neurological Norepinephrine/pharmacology Organ Culture Techniques Pineal Gland/drug effects,enzymology,metabolism Rats Rats, Inbred Strains Serotonin/pharmacology Time Factors Transferases/metabolism Tritium
Chemicals
Culture Media Indoles Tritium Serotonin Methionine Cyclic AMP Transferases Melatonin Norepinephrine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Klein D C
Weller J
References (37)
37 references, click to expand
  1. The exzymic acetylation of serotonin and other naturally occurring amines.
    Biochim Biophys Acta. 1961 Nov 25;54:190-2 PMID: 14005907
  2. Formation of melatonin and 5-hydroxyindole acetic acid from 14C-tryptophan by rat pineal glands in organ culture.
    Nature. 1968 Mar 9;217(5132):953-4 PMID: 5300432
  3. The fluorometric determination of indolealkylamines in brain and pineal gland.
    Adv Pharmacol. 1968;6(Pt A):71-7 PMID: 5664059
  4. The role of cyclic AMP in hormone actions.
    Adv Enzyme Regul. 1968;6:357-89 PMID: 4306736
  5. Biosynthesis of melatonin: enzymic conversion of serotonin to N-acetylserotonin.
    Biochim Biophys Acta. 1960 Sep 23;43:352-3 PMID: 13784117
  6. Indole metabolism in the pineal gland: a circadian rhythm in N-acetyltransferase.
    Science. 1970 Sep 11;169(3950):1093-5 PMID: 4915470
  7. Adenyl cyclase activity in rat pineal gland: effects of chronic denervation and norepinephrine.
    Science. 1967 Jun 30;156(3783):1750-2 PMID: 4305967
  8. NEURAL AND PHOTIC REGULATION OF 5-HYDROXYTRYPTOPHAN DECARBOXYLASE IN THE RAT PINEAL GLAND.
    Nature. 1964 Aug 29;203:981-2 PMID: 14203521
  9. Light-induced changes in pineal hydroxyindole-O-methyltransferase: abolition by lateral hypothalamic lesions.
    Science. 1966 Nov 18;154(3751):898-9 PMID: 4886825
  10. The development, topographical relations and innervation of the epiphysis cerebri in the albino rat.
    Z Zellforsch Mikrosk Anat. 1960;52:163-215 PMID: 13751359
  11. Submicroscopic localization of norepinephrine in sympathetic nerves of rat pineal.
    J Pharmacol Exp Ther. 1966 Jul;153(1):42-7 PMID: 5921356
  12. Central control of the pineal gland: visual pathways.
    Arch Neurol. 1968 Feb;18(2):208-18 PMID: 5688808
  13. CONTROL OF HYDROXYINDOLE O-METHYLTRANSFERASE ACTIVITY IN THE RAT PINEAL GLAND BY ENVIRONMENTAL LIGHTING.
    J Biol Chem. 1965 Feb;240:949-54 PMID: 14275158
  14. CONTROL OF THE CIRCADIAN RHYTHM IN SEROTONIN CONTENT OF THE RAT PINEAL GLAND.
    Proc Natl Acad Sci U S A. 1965 Feb;53:301-5 PMID: 14294060
  15. Visual pathway mediating pineal response to environmental light.
    Science. 1967 Jan 13;155(3759):220-3 PMID: 6015532
  16. Turnover rate measurements of brain serotonin in unanesthetized rats.
    Adv Biochem Psychopharmacol. 1969;1:91-109 PMID: 4947259
  17. Purification and properties of hydroxyindole-O-methyl transferase.
    J Biol Chem. 1961 Jan;236:211-3 PMID: 13685335
  18. Cyclic adenosine monophosphate: stimulation of melatonin and serotonin synthesis in cultured rat pineals.
    Science. 1969 Oct 24;166(3904):519-20 PMID: 4309627
  19. Pineal gland in organ culture. I. Inhibition by harmine of serotonin-14C oxidation, accompanied by stimulation of melatonin-14C production.
    Mol Pharmacol. 1970 Mar;6(2):164-71 PMID: 5418234
  20. Effect of phosphate, calcium and magnesium on bone resorption and hormonal responses in tissue culture.
    Endocrinology. 1969 Sep;85(3):446-52 PMID: 5793028
  21. CIRCADIAN AND ESTROUS RHYTHMS IN PINEAL MELATONIN AND 5-HYDROXY INDOLE-3-ACETIC ACID.
    Proc Soc Exp Biol Med. 1964 Mar;115:710-3 PMID: 14155806
  22. Pineal gland: dibutyryl cyclic adenosine monophosphate stimulation of labeled melatonin production.
    Science. 1970 Mar 27;167(3926):1738-40 PMID: 4313580
  23. Stimulation of C14-melatonin synthesis from C14-tryptophan by noradrenaline in rat pineal in organ culture.
    Proc Natl Acad Sci U S A. 1969 Feb;62(2):544-9 PMID: 5256232
  24. BONE RESORPTION IN TISSUE CULTURE. FACTORS INFLUENCING THE RESPONSE TO PARATHYROID HORMONE.
    J Clin Invest. 1965 Jan;44:103-16 PMID: 14254246
  25. Central control of noradrenaline content in rat pineal and submaxillary glands.
    Life Sci. 1966 Jan;5(2):155-61 PMID: 5942051
  26. Kinetic and fluorescent histochemical analysis of the serotonin compartments in rat pineal gland.
    Eur J Pharmacol. 1969 Mar;5(4):348-56 PMID: 5786358
  27. The culture of mature organs in a synthetic medium.
    Exp Cell Res. 1959 Jan;16(1):118-47 PMID: 13639945
  28. LOCALIZATION OF MELATONIN IN THE NERVOUS SYSTEM.
    J Neurochem. 1964 Jun;11:489-91 PMID: 14184979
  29. Pineal, neural and photic control of reproductive organ size in early androgen-treated male rats.
    Neuroendocrinology. 1968;3(4):246-55 PMID: 5700737
  30. Localizing tritiated norepinephrine in sympathetic axons by electron microscopic autoradiography.
    Science. 1962 Oct 19;138(3538):440-2 PMID: 14001559
  31. Electrophysiological evidence for the action of light on the pineal gland in the rat.
    Experientia. 1970 Mar 15;26(3):267-9 PMID: 5417490
  32. Melatonin synthesis: adenosine 3',5'-monophosphate and norepinephrine stimulate N-acetyltransferase.
    Science. 1970 May 22;168(3934):979-80 PMID: 4314985
  33. The pineal gland and gonadal development in male rats and hamsters.
    Fertil Steril. 1968 Nov-Dec;19(6):1009-17 PMID: 5748710
  34. Endocrine aspects of the mammalian pineal gland: a review.
    Neuroendocrinology. 1969;5(3):219-55 PMID: 4903104
  35. Neurobiological significance of cyclic 3',5'-adenosine monophosphate.
    Adv Biochem Psychopharmacol. 1969;1:131-64 PMID: 4335476
  36. SEROTONIN RHYTHM IN THE PINEAL ORGAN: CONTROL BY THE SYMPATHETIC NERVOUS SYSTEM.
    Science. 1964 Oct 9;146(3641):253-4 PMID: 14185321
  37. Thin-layer chromatographic separation of pineal gland derivatives of serotonin-14C.
    Anal Biochem. 1969 Oct 1;31(1):480-3 PMID: 5382627
Article Info
Journal
In vitro
Abbr.
In Vitro
ISSN
0073-5655
DOI
10.1007/BF02617764
Published
1970-00-00
Pages
197-204
Language
English
Region
United States
NLM ID
0063733
Subset
IM
External Links
PubMed source DOI: 10.1007/BF02617764
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