Factors influencing the inhibitory effect of carbon monoxide on cytochrome P-450-catalyzed mixed function oxidation reactions.

Animals Anisoles/metabolism Binding Sites Carbon Monoxide/administration & dosage,pharmacology Cytochromes/antagonists & inhibitors,metabolism Electron Transport Electron Transport Complex IV/metabolism In Vitro Techniques Methylation Metyrapone/metabolism Microsomes, Liver/drug effects,enzymology,metabolism Morphine/metabolism Nitroso Compounds/metabolism Oxidation-Reduction Phenobarbital/pharmacology Rats

Anisoles Cytochromes Nitroso Compounds Morphine Carbon Monoxide Electron Transport Complex IV Phenobarbital Metyrapone