Studies on the active site of clostripain. The specific inactivation by the chloromethyl ketone derived from -N-tosyl-L-lysine.

Acetone Alkylation Amidines Arginine Benzoates Binding Sites Bromine Chlorine Chromatography Clostridium/enzymology Dithiothreitol Endopeptidases/isolation & purification Enzyme Activation Hydroxyapatites Iodoacetates Ketones Kinetics Lysine Microbial Collagenase Phenylalanine Protease Inhibitors Protein Binding Tosyl Compounds Tritium

Amidines Benzoates Hydroxyapatites Iodoacetates Ketones Protease Inhibitors Tosyl Compounds Tritium Acetone Phenylalanine Chlorine Arginine Endopeptidases Microbial Collagenase Lysine Bromine Dithiothreitol