Ultrastructural characteristics of the "hairy cells" of leukemic reticuloendotheliosis.

The American journal of pathology ·Vol. 67 ·No. 2 ·1972-05-00 ·Pages 361-70

Katayama I, Li CY, Yam LT

Abstract

The pathognomonic neoplastic reticulum cells, or "hairy cells" of leukemic reticuloendotheliosis from 6 patients were studied with the electron microscope. These cells demonstrated characteristic ultrastructural features which were distinctly different from those of lymphocytes, monocytes, or histiocytes. In 3 patients a distinctive ribosome-lamella complex was found. The biologic significance of this unusual cytoplasmic inclusion is still unknown. Its frequent presence in leukemic reticuloendotheliosis and its rarity in other neoplastic diseases suggest a substantial yet unexplained relationship between this complex and leukemic reticuloendotheliosis.

MeSH Terms

Bone Marrow Cells Humans Inclusion Bodies Leukemia, Myeloid/pathology Leukocyte Count Lymphatic Diseases/pathology Microscopy, Electron Neoplastic Cells, Circulating/pathology Ribosomes Spleen/pathology

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Katayama I

Li C Y

Yam L T

References (18)

18 references, click to expand

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Article Info

Journal

The American journal of pathology

Abbr.

Am J Pathol

ISSN

0002-9440

Published

1972-05-00

Pages

361-70

Language

English

Region

United States

NLM ID

0370502

PMCID

PMC2032609

Subset

External Links

PubMed source PMC Full Text View journal details

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Ultrastructural characteristics of the "hairy cells" of leukemic reticuloendotheliosis.

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