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PMID: 4344304 Published · ppublish English Journal Article

Electron microscopy observations on a new herpes-type virus isolated from Iguana iguana and propagated in reptilian cells in vitro.

Infection and immunity ·Vol. 5 ·No. 4 ·1972-04-00 ·Pages 570-82

Zeigel RF, Clark HF

Abstract

Ultrastructural observations on a new viral isolate, designated iguana virus, indicate that it is consistently present in intranuclear inclusions, possesses a +/- 115-nm nucleocapsid, ranges from 165 to 300 nm in diameter in the enveloped form, and exhibits cubic symmetry (probably 162 capsomeres). It is concluded that it is a herpes-type virus, the morphological evidence being in agreement with and supporting the biological and physical characteristics presented by Clark and Karzon. Several fine-structural features, among them the encapsidization of small 35-nm hexagonal bodies and the viral membrane envelope enclosure of cell-derived moieties are presented and discussed.

MeSH Terms
Animals Cell Membrane Cell Nucleus Cells, Cultured Endoplasmic Reticulum Heart Herpesviridae/isolation & purification Herpesviridae Infections/microbiology,veterinary Lizards Microscopy, Electron Turtles Ultracentrifugation
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Zeigel R F
Clark H F
References (20)
20 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.5.4.570-582.1972
Published
1972-04-00
Pages
570-82
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC422408
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.5.4.570-582.1972 PMC Full Text View journal details
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