Activity of foot-and-mouth disease virus RNA-dependent RNA polymerase in vitro: inhibition by polyamines and poly(amino acid)s.

Aphthovirus/enzymology Arginine Cadaverine/pharmacology DNA DNA-Directed RNA Polymerases/antagonists & inhibitors,metabolism Heparin/pharmacology Hydrogen-Ion Concentration Kinetics Lysine Ornithine Peptides/pharmacology Polyamines/pharmacology Putrescine/pharmacology RNA, Viral/biosynthesis Spectrophotometry, Ultraviolet Spermine/pharmacology Time Factors

Peptides Polyamines RNA, Viral Spermine Heparin DNA Arginine Ornithine DNA-Directed RNA Polymerases Lysine Cadaverine Putrescine