The activation of adenylate cyclase. II. The postulated presence of (A) adenylate cyclase in a phospho (inhibited) form (B) a dephospho (activated) form with a cyclic adenylate stimulated membrane protein kinase.

Adenylyl Cyclases/blood,metabolism Animals Blood Platelets/cytology,drug effects,enzymology Cell Membrane/drug effects,enzymology Cyclic AMP/metabolism,pharmacology Cytosol/enzymology Dogs Enzyme Activation Fluorides/pharmacology Kinetics Leukocytes/cytology,drug effects,enzymology Phosphorus Isotopes Phosphotransferases/metabolism Prostaglandins/pharmacology Protein Kinases/metabolism Rabbits Subcellular Fractions/metabolism Time Factors Tritium

Phosphorus Isotopes Prostaglandins Tritium Cyclic AMP Phosphotransferases Protein Kinases Adenylyl Cyclases Fluorides