Synthesis and biochemical studies of various 8-substituted derivatives of guanosine 3',5'-cyclic phosphate, inosine 3',5'-cyclic phosphate, and xanthosine 3',5'-cyclic phosphate.

Alcohols Amines Animals Benzene Derivatives Benzyl Compounds Cattle Chemical Phenomena Chemistry Cyclic GMP/metabolism Deamination Hydrogenation Inosine Nucleotides/metabolism Lung/enzymology Methylamines Myocardium/enzymology Nephropidae Nucleotides, Cyclic/metabolism,pharmacology Phosphodiesterase Inhibitors Protein Kinases/metabolism Rabbits Structure-Activity Relationship Sulfides

Alcohols Amines Benzene Derivatives Benzyl Compounds Inosine Nucleotides Methylamines Nucleotides, Cyclic Phosphodiesterase Inhibitors Sulfides Protein Kinases Cyclic GMP