Action of magnesium ion on diphosphopyridine nucleotide-linked isocitrate dehydrogenase from bovine heart. Characterization of the forms of the substrate and the modifier of the reaction.

Adenosine Diphosphate/administration & dosage,pharmacology Animals Binding Sites Binding, Competitive Cattle Enzyme Activation Hydrogen-Ion Concentration Isocitrate Dehydrogenase/antagonists & inhibitors,metabolism Isocitrates/administration & dosage,metabolism,pharmacology Kinetics Magnesium/administration & dosage,metabolism,pharmacology Manganese/pharmacology Mathematics Models, Chemical Myocardium/enzymology NAD Protein Binding/drug effects Protein Conformation

Isocitrates NAD Manganese Adenosine Diphosphate Isocitrate Dehydrogenase Magnesium